Carlos G. Arcangeli, MD & Mark A. Rosen, MD

Adult and Pediatric Urology

Causes of Erectile Dysfunction

There are many factors that contribute to erection and ejaculation. Physical and mental stimulants, hormones, neural transmissions and feedback, muscle contractions and relaxations, and cardiovascular blood flow all work together to create and maintain an erection leading to ejaculation. When any of these processes are disrupted, it can cause erectile dysfunction (ED).

The causes of ED are generally divided into two major categories: Those that are psychological in nature and those that are physical (or organic) in nature.

Psychological Causes

Psychological causes are based on cultural expectations, mental distractions, personal desires and sometimes mental illness. Psychological causes of ED include:

Physical Causes of ED

Physical causes of ED generally affect a particular step in the erection sequence. The most common physical causes for ED are:

Diabetes

Diabetes is one of the most common causes of ED. Nerves or blood vessels that control the flow of blood to the penis may become permanently damaged as a result of diabetes. Damage to either can lead to ED.

Cardiovascular Disease

Vascular problems, such as hardening of the arteries, can slow the blood flowing into the penis, making it difficult to get or keep an erection. (Since this affects the small vessels before it affects the bigger vessels, finding an ED problem could signal the presence of a cardiovascular disease.)

Sometimes, the mechanism that compresses the veins to trap blood in the penis during an erection doesn’t work properly, so men cannot maintain an erection long enough for sexual intercourse.

Drug Therapies

Drugs, including some prescriptions for high blood pressure, depression, and a number of other conditions, may cause ED by interfering with the nerve impulses or blood flow to the penis. The following drugs can cause ED.

Important: Medications should never be changed without your doctor’s permission. Talk to your doctor about any concerns you have regarding the potential effects of medication on ED.

Alcoholism and Smoking

Alcoholism disrupts hormone levels and can lead to permanent nerve damage, causing impotence. Smoking may lead to vascular disease or other health problems, which may cause ED.

Hormone Problems

Certain diseases, such as kidney failure and liver disease can disrupt the balance of hormones, which control erections. Low levels of testosterone can also be a factor.

Body Trauma

Traumas to the body can result in ED. Some of these traumas include:

Priapism

Priapism is an erection that lasts longer than normal and is caused by reasons other than sexual desire. If an erection lasts longer than four hours, it can cause tissue injury, which will result in ED. Causes of priapism include:

Surgery

Surgery that interrupts blood flow or damages nerve function may result in ED. Some of these surgeries include:

Effects of Aging

It is estimated that 65 percent of men over age 65 have some type of ED. Statistically, the number of men experiencing ED rises as their age increases. However, age alone does not cause ED. It is simply that older men are more likely to have the illnesses and treatments (such as prostate surgery) that can cause ED.

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